3-Hydroxyisobenzofuran-1(3H)-one

3-Hydroxyphthalide is the cyclic hydroxy-lactone form associated with ortho-formylbenzoic acid chemistry. Its hydroxy-bearing carbon provides a site for replacement or derivatization, while the lactone carbonyl contributes to ring-opening and heterocycle-forming transformations. This compact fused-ring structure places two oxygen-containing reaction centers beside one another.

The cyclic lactol is closely related to the open-chain ortho-formylbenzoic-acid structure. Its C3 center can react with suitable nucleophiles to build substituted phthalides, while nitrogen-containing reagents enable ring-conversion chemistry. The fused aromatic lactone supplies a compact scaffold for these transformations, combining an existing carbonyl-containing ring with an accessible substitution site.

Typical Applications

• C3-Substituted phthalides: Used in reactions that replace or transform the C3 hydroxyl, preparing substituted lactones while retaining the fused benzene–lactone framework.
• Fused nitrogen-heterocycle precursors: Used in carbonyl-condensation and ring-conversion chemistry to introduce nitrogen-containing functionality into structures derived from the ortho-formylbenzoic-acid skeleton.

Specifications

Specifications describe the standard grade. Tolerance, test method and documentation package are confirmed per order.