5-Methoxy-1-[4-(trifluoromethyl)phenyl]pentan-1-one

5-Methoxy-1-[4-(trifluoromethyl)phenyl]pentan-1-one is a ketone intermediate associated with fluvoxamine synthesis. Its carbonyl supplies the site for oxime formation, while the methoxyalkyl and trifluoromethylphenyl groups transfer the required carbon skeleton. The ketone therefore combines a reactive center with two preassembled fragments that remain in downstream oxime derivatives.

The selected material precedes introduction of the aminoethoxy-containing oxime substituent. Converting the carbonyl to an oxime establishes a new nitrogen–oxygen functional group and introduces geometric-isomer considerations absent from the starting ketone. Subsequent oxygen functionalization and amine deprotection complete later route stages. This places the compound upstream of fluvoxamine free base and its final maleate salt.

Typical Applications

• Fluvoxamine oxime-intermediate production: Used in oximation routes that convert the aryl ketone into the corresponding oxime while retaining the terminal methoxy group and para-trifluoromethyl aromatic substitution.
• Substituted oxime-ether synthesis: Used as the ketone feedstock in sequences that form the oxime and then introduce an oxygen-linked side chain, preparing fluvoxamine-related derivatives.

Specifications

Specifications describe the standard grade. Tolerance, test method and documentation package are confirmed per order.