Methyl 3-formyl-2-nitrobenzoate

Methyl 3-formyl-2-nitrobenzoate is a multifunctional aromatic building block with an aldehyde, a nitro group and a protected carboxyl function. The aldehyde supports condensation and carbon-chain extension, while nitro reduction provides access to an aniline. Their neighboring positions allow downstream ring construction, with the methyl ester carrying an additional carbonyl substituent through the sequence.

The selected material is the methyl ester rather than the free benzoic acid. This protection state separates reactions of the aldehyde from later conversion of the carboxyl group. The substitution pattern is particularly useful when a nitrogen-containing fused ring must be constructed beside an existing ester. Each functional group therefore contributes a different stage of synthetic elaboration.

Typical Applications

• Nitrogen-containing fused-ring intermediates: Used in routes that elaborate the formyl group and convert the neighboring nitro functionality into a nitrogen-bearing ring precursor, retaining the aromatic ester.
• Substituted aromatic condensation products: Used as an aldehyde component for imine or carbon–carbon bond formation, introducing a nitro- and ester-substituted aromatic fragment into downstream molecules.

Specifications

Specifications describe the standard grade. Tolerance, test method and documentation package are confirmed per order.