2-(4-Formylphenyl)acetic acid

2-(4-Formylphenyl)acetic acid is a bifunctional aromatic intermediate with a benzaldehyde group and an acetic-acid side chain. The aldehyde supports imine or reductive-amination chemistry, while the acid provides an independent site for amide formation. This allows a para-disubstituted aromatic fragment to be assembled with different nitrogen-containing connections at its two ends.

The selected material is the free acid, retaining the methylene between the ring and carboxyl group. Amidation can introduce an N-ethyl side-chain precursor, while the formyl group remains available for attachment to a second fragment. Subsequent transformations of the amide can change the side-chain oxidation state. These stages make the compound relevant to elacestrant-related fragment routes and other substituted phenylacetic-acid chemistry.

Typical Applications

• N-Ethyl phenylacetamide intermediates: Used in amidation with ethylamine to install an N-ethyl amide on the acetic-acid side chain while preserving the para-formyl functionality.
• Benzyl-linked aromatic fragments: Used as the aldehyde component in condensation or reductive amination, creating a benzyl–nitrogen connection while retaining the acid or its protected derivative for later conversion.

Specifications

Specifications describe the standard grade. Tolerance, test method and documentation package are confirmed per order.