(R)-3-(4-Bromophenyl)-5-hydroxy-5-methylhexanoic acid

(R)-3-(4-Bromophenyl)-5-hydroxy-5-methylhexanoic acid is a chiral hydroxy-acid building block containing an aryl bromide. The carboxyl group supplies an acyl-derivatization site, while the brominated aromatic ring allows separate carbon-framework elaboration. Its tertiary alcohol and R-configured aryl-bearing center provide additional structural features carried into downstream intermediates.

The free-acid form can be converted into esters or amides without changing the intended aromatic connection point. Alternatively, coupling at the aryl bromide extends the carbon skeleton while the acid is protected or otherwise accommodated by the reaction. These independent sites make the compound useful for staged synthesis of chiral aryl-containing derivatives, with the hydroxyl group available for protection or subsequent transformation.

Typical Applications

• Chiral hydroxy-acid derivatives: Used in esterification or amide-coupling sequences to introduce an alcohol- or amine-derived substituent at the carboxyl group.
• Aryl-substituted chiral intermediates: Used in coupling reactions at the para-brominated ring, extending the aromatic fragment while retaining the hydroxy-acid-derived chiral side chain.

Specifications

Specifications describe the standard grade. Tolerance, test method and documentation package are confirmed per order.