trans-4-Aminocyclohexanol

Trans-4-Aminocyclohexanol is a bifunctional cycloaliphatic building block with an amino group and a hydroxyl group in a defined trans relationship. The amine provides a site for acylation, carbamate formation or other nitrogen substitution, while the alcohol supports oxygen functionalization. The cyclohexane ring holds the two substituents in a stereochemically specified 1,4 arrangement.

The selected material is the free amino alcohol, allowing either functional group to be addressed with suitable protection of the other when necessary. It introduces a polar, saturated-ring linker into pharmaceutical and fine-chemical intermediates. Nitrogen derivatization can retain a free hydroxyl for later attachment, while oxygen derivatization can preserve or subsequently expose the amino group. The stated trans identity refers to the starting ring substitution pattern.

Typical Applications

• Hydroxycyclohexyl amides and carbamates: Used as an amine partner in acylation or carbamylation to introduce a trans-4-hydroxycyclohexyl substituent into a target intermediate.
• Amino-functional cyclohexyl ethers: Used in alcohol functionalization after appropriate nitrogen protection to construct oxygen-linked derivatives, followed by exposure or further modification of the amine.

Specifications

Specifications describe the standard grade. Tolerance, test method and documentation package are confirmed per order.