Palmitoyl tripeptide-1

CAS No.

147732-56-7

Synonyms

Pal-GHK; Palmitoyl-Gly-His-Lys; Palmitoyl oligopeptide (GHK); also listed as Palmitoyl Tripeptide-1 (Pal-GHK)

Molecular formula

C30H54N6O5

Molecular weight

578.79 g/mol

Grade

Cosmetic grade

Packaging

Aluminum foil laminate bag / Fiber drum with PE liner
SKU FM-309 Category

Chemical Product Description & Applications

Palmitoyl tripeptide-1 is a lipid-modified cosmetic peptide based on the sequence glycine-histidine-lysine. The peptide portion is used in skin-conditioning and anti-aging ingredient systems associated with extracellular-matrix signaling, while the palmitoyl group changes its affinity for lipid environments. These features support its use in formulations aimed at smoother-looking skin and improvement in the appearance of fine lines.

The single-peptide powder is a concentrated formulation input that is incorporated through a suitable solvent or delivery vehicle. The carrier distributes the lipid-modified peptide through the finished product and permits accurate blending with other actives. Commercial peptide solutions may also contain polymers, glycols or additional peptides, whereas this powder allows the peptide and vehicle contributions to be selected independently.

Typical Applications

  • Peptide facial serums: Used as a defined single-peptide input in anti-aging serum formulations. It allows the formulator to set the peptide contribution independently from the solvent and other active ingredients.
  • Fine-line care creams: Used in face and neck emulsions designed around a peptide-based smoothing concept. The peptide is delivered within a moisturizing cream vehicle rather than functioning as the cream’s emulsifier or texture builder.
  • Eye-contour peptide formulations: Used in eye-area creams and serums targeting the appearance of fine lines. It supplies a skin-conditioning peptide component alongside the product’s separate moisturizing and emollient system.

Specifications

Parameter Specification Test Method
Appearance White to off-white powder Visual inspection
Identification Consistent with authenticated reference FTIR fingerprint comparison
Peptide identity Molecular ion and sequence consistent with reference LC-MS with peptide fragmentation
Chromatographic purity ≥95.0 area% HPLC-UV at peptide-bond wavelength
Peptide content ≥80.0% w/w Amino acid analysis after hydrolysis
Water ≤8.0% w/w Karl Fischer titration

Specifications describe the standard grade. Tolerance, test method and documentation package are confirmed per order.

Documents & Handling

Packaging

Aluminum foil laminate bag / Fiber drum with PE liner

What You Get With This Product

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CoA

Certificate of Analysis

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TDS

Technical Data Sheet

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SDS

Safety Data Sheet

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