3,3-Dimethylbutyryl chloride

3,3-Dimethylbutyryl chloride is an acid chloride used to introduce the 3,3-dimethylbutanoyl group into organic molecules. Its reactive acyl chloride function enables formation of amides and esters, while the branched carbon skeleton supplies a bulky, hydrophobic structural fragment. The compound is also called tert-butylacetyl chloride.

The structure contains a methylene group between the tert-butyl group and the carbonyl carbon. This makes it distinct from pivaloyl chloride, whose tert-butyl group is attached directly to the carbonyl. As a moisture-sensitive liquid intermediate, it is used in controlled organic synthesis rather than aqueous formulation. Product value lies in the combination of a reactive acylating group and a defined branched side chain.

Typical Applications

• Branched amide intermediate synthesis: Used to acylate amine-containing intermediates when the target structure requires a 3,3-dimethylbutanamide unit. This provides a defined side chain for fine-chemical and pharmaceutical intermediate development.
• Specialty ester manufacture: Used to introduce the 3,3-dimethylbutanoyl group into alcohol-containing substrates. The resulting ester structures are relevant to specialty chemical synthesis and comparison of branched acyl derivatives.

Specifications

Specifications describe the standard grade. Tolerance, test method and documentation package are confirmed per order.